Total Knee Replacement Market – By Product, By Device Type, By Component, By Implant Type, By Design, By Surgery Type, By Fixation Material, By Material, By Polyethylene Inserts, By End Use, & Global Forecast, 2024 – 2032

Total Knee Replacement Market Size

The global total knee replacement market was valued at USD 9.4 billion in 2023 and is expected to exhibit growth at a CAGR of 5.1% from 2024 to 2032. The rising prevalence of arthritis and osteoporosis, combined with increasing infection rates, is leading to a surge in knee revision procedures, which is significantly driving market growth.  
 

As the global population ages and life expectancy rises, the number of individuals affected by these conditions is expected to increase, boosting demand for knee replacement procedures. Rising obesity rates, a key risk factor for osteoarthritis, and the widespread occurrence of osteoporosis, especially in rheumatoid arthritis patients, further intensify the need for knee replacements.
 

According to the CDC, between 2019 and 2021, around 21.2% of U.S. adults (53.2 million) reported being diagnosed with arthritis. These trends, coupled with the growing incidence of infections requiring knee revisions, suggest a continuing rise in procedures, emphasizing the need for public health strategies to manage the burden on healthcare systems and improve patient outcomes.
 

Total knee replacement, also known as total knee arthroplasty (TKA), is a surgical procedure that involves replacing the damaged surfaces of the knee joint with artificial components. This procedure is primarily performed to relieve pain and restore function in individuals suffering from severe knee arthritis, particularly osteoarthritis, rheumatoid arthritis, or post-traumatic arthritis, when conservative treatments have failed.
 

Total Knee Replacement Market Trends

Technological advancements in total knee replacement are significantly driving market growth by enhancing surgical precision, improving patient outcomes, and increasing patient satisfaction.
 

• Robotic systems, such as the VELYS Robotic-Assisted Solution, allow for personalized surgical planning and execution. These systems create 3D models of the patient’s knee, enabling surgeons to tailor the procedure to individual anatomy and improve implant positioning accuracy. This technology is associated with less tissue disruption and faster recovery times compared to traditional methods.
   
• Additionally, development of smart implants, for instance, the Persona IQ implant that features integrated sensors that monitor patient activity, such as range of motion and walking speed. This data is transmitted to healthcare providers, allowing for real-time monitoring of recovery and personalized rehabilitation plans. This innovation enhances patient engagement and helps ensure optimal recovery outcomes.
   
• Moreover, the Patient-Specific Instrumentation (PSI) technology involves creating customized surgical instruments based on preoperative imaging. PSI aims to improve the accuracy of implant placement and alignment, which can lead to better functional outcomes and reduced postoperative complications. These advancements not only improve surgical outcomes but also cater to the increasing demand for knee replacements.
   

Total Knee Replacement Market Analysis

Based on product, the market is classified into primary knee replacement systems, partial knee replacement systems, and revision knee replacement systems. The primary knee replacement systems segment generated the highest revenue of USD 7.7 billion in 2023.
 

• Primary knee replacement systems are used in initial, first-time surgeries, which are far more common compared to revision or partial procedures. As osteoarthritis and other joint-degenerative conditions become more prevalent, more patients undergo first-time total knee replacement surgeries, making this segment the largest in the market.
   
• Additionally, primary knee replacement systems are suitable for a broad range of patients with severe knee joint damage caused by arthritis, trauma, or degenerative diseases, thus contributing to their dominance in the market.
   

Based on device type, the total knee replacement market is categorized into three-compartmental knee implants, bicompartmental knee implants, and unicompartmental knee implants. The three-compartmental knee implants segment dominated the market by obtaining 77.4% of market shares in 2023.
 

• Three-compartmental knee implants are used in total knee replacement surgeries, where all three compartments of the knee (medial, lateral, and patellofemoral) are replaced. These surgeries are more common, as they address advanced or severe cases of knee joint degeneration, such as osteoarthritis, which affects all compartments of the knee.
   
• Compared to unicompartmental or bicompartmental procedures, total knee replacements are more frequently performed because they provide a long-term solution for patients with extensive knee damage. Most patients presenting with severe arthritis or joint deterioration require full knee replacement, making three-compartmental implants the most widely used.
   

Based on component, the total knee replacement market is classified into femoral, tibial, and patellar. The femoral segment is anticipated to generate the highest revenue of USD 7.3 billion during the forecast period.
 

• The femoral component is the largest and most complex part of the knee implant, as it replaces the end of the femur (thigh bone) and bears significant weight and movement. As a result, it requires more intricate design and material, leading to its dominance in terms of usage and cost.
   
• Additionally, the femoral component plays a crucial role in joint movement and articulation, directly interacting with the tibial component to enable smooth motion. Its critical function in the overall success of knee replacement surgeries makes it the most frequently used and essential component in total knee replacement procedures.
   

Based on implant type, the total knee replacement market is categorized into fixed-bearing implants, mobile-bearing implants, medial pivot implants, and other implant types. The fixed-bearing implants segment is anticipated to grow with the CAGR of 3.4% during forecast period.
 

• Fixed-bearing implants are more commonly used in total knee replacement surgeries due to their straightforward design, durability, and ease of implantation. The implant's fixed design, where the polyethylene insert is securely attached to the tibial component, provides reliable long-term outcomes for most patients.
   
• Additionally, fixed-bearing implants are generally more cost-effective compared to mobile-bearing or other advanced implant types, making them a preferred choice for both healthcare providers and patients. Many surgeons are more familiar with the fixed-bearing approach, further contributing to its widespread use.
   

Based on design, the total knee replacement market is classified into posterior stabilized design, cruciate retaining design, and other designs. The posterior stabilized design segment generated the highest revenue of USD 4.7 billion in 2023.
 

• The posterior stabilized design is often chosen for patients with more severe knee damage or where the posterior cruciate ligament (PCL) is either too damaged to preserve or needs to be removed. This design offers enhanced stability and prevents excessive forward movement of the tibia during knee flexion. This added stability makes it a popular choice.
   
• The posterior stabilized design is more widely applicable to a broader range of patients because it can be used even when the PCL is not functioning well. This versatility, combined with the predictable outcomes and reliable performance of the PS implants, makes it the dominant choice for many surgeons and patients, particularly in cases requiring full knee replacement.
   

Based on surgery type, the total knee replacement market is categorized into traditional surgery type and technology assisted surgery type. The traditional surgery type segment dominated the market by obtaining 87% of market shares in 2023.
 

• Traditional knee replacement surgery, which is performed manually without advanced technological assistance, has been the standard approach for many years. Surgeons have extensive experience with this method, and it remains the most widely performed due to its long track record of success and reliability.
   
• Traditional surgery is generally more cost-effective compared to technology-assisted surgery, which often involves the use of robotic systems or computer navigation. Many healthcare facilities, especially in regions with limited access to advanced technology, still rely on traditional methods due to lower costs and availability.
   

Based on fixation material, the total knee replacement market is categorized into cemented, cementless, and hybrid. The cemented segment is anticipated to grow with the CAGR of 4.9% during the forecast period.
 

• Cemented fixation has been the standard technique for many years and is widely preferred by surgeons due to its reliability and long-term success. In this method, bone cement is used to secure the implant to the bone, providing immediate stability and allowing for quicker post-surgery recovery.
   
• Additionally, cemented implants are suitable for a wide variety of patients, including older adults and those with weaker or less dense bones, which is common in patients undergoing knee replacement surgeries. Its versatility and proven effectiveness make cemented fixation the go-to option for many healthcare providers.
   

Based on material, the total knee replacement market is categorized into metal-on-plastic,
 

ceramic-on-plastic, metal-on-metal, and ceramic-on-ceramic. The metal-on-plastic segment dominated the market by obtaining 59.2% of market share in 2023.
 

• The metal-on-plastic combination has been extensively studied and has a wealth of long-term clinical data demonstrating its reliability and effectiveness. This material combination is preferred in most total knee replacement surgeries due to its ability to provide smooth joint movement while minimizing complications such as implant failure or wear over time.
   
• Compared to other materials, metal-on-plastic implants have a lower risk of complications such as metal ion release or ceramic fractures, which can be concerned with metal-on-metal or ceramic-based implants. The combination of a smooth metal surface with a durable plastic insert minimizes the likelihood of post-surgical issues, making it a safer choice for long-term joint function.
   

Based on polyethylene inserts, the total knee replacement market is classified into antioxidant polyethylene inserts, highly cross-linked polyethylene inserts, and conventional polyethylene inserts. The antioxidant polyethylene inserts segment is anticipated to generate high revenue of USD 8.3 billion in forecast period.
 

• Antioxidant polyethylene inserts are infused with stabilizing agents, such as vitamin E, that prevent the material from oxidizing over time. The increased durability of antioxidant inserts makes them highly appealing for surgeons aiming for long-lasting knee implants, reducing the need for revision surgeries.
   
• Antioxidant polyethylene minimizes the formation of wear particles, which can lead to osteolysis (bone loss) and implant loosening. This enhanced performance, combined with its ability to retain the material’s mechanical strength over the long term, has positioned antioxidant polyethylene as the preferred choice, especially for younger, more active patients who require longer-lasting implants.
   

Based on end-use, the total knee replacement market is segmented into hospitals, ambulatory surgical centers, and other end-users. The hospitals segment dominated the market in 2023 and is anticipated to reach USD 11.3 billion by 2032.
 

• Hospitals typically have the necessary infrastructure, equipment, and skilled orthopedic surgeons required for complex procedures like total knee replacements. They are also equipped to handle complications and provide comprehensive post-operative care, including rehabilitation, which makes them the preferred choice for both patients and healthcare providers.
   
• Additionally, hospitals, particularly large and multi-specialty centers cater to a broader range of patients, including those with co-morbidities or more complicated medical conditions, who may not be suitable for outpatient surgeries. Their ability to manage complex cases and offer in-patient care makes hospitals the dominant end-use segment for total knee replacement procedures.
   

North America total knee replacement market accounted for USD 5.1 billion market revenue in 2023 and is anticipated to grow at a CAGR of 3.8% between 2024 and 2032 period.
 

• North America sees a high prevalence of osteoarthritis, particularly among aging populations. The sedentary lifestyle and obesity rates in the region further exacerbate joint degeneration, contributing to the growing number of total knee replacement surgeries. The prevalence of osteoarthritis in North America is significantly higher than in many other regions, directly driving the demand for knee replacements.
   
• Additionally, the adoption of advanced technologies such as robotic-assisted surgery and custom-made knee implants has gained significant traction in North America. These technologies offer more precise and personalized procedures, leading to better patient outcomes and shorter recovery times, further boosting the adoption of total knee replacement procedures in the region.
   

U.S. total knee replacement market accounted for USD 4.8 billion market revenue in 2023 and is estimated to hold substantial share between 2024 and 2032.
 

• The U.S. has a rapidly aging population, reaching an age where joint degeneration becomes more prevalent. This demographic shift is directly linked to an increased demand for total knee replacement surgeries.
   
• Moreover, the U.S. healthcare system offers extensive coverage for joint replacement surgeries through Medicare and private health insurance, making knee replacement procedures more accessible to a larger portion of the population. This accessibility, coupled with better awareness and early diagnosis of joint issues, is driving the growth of the market in the U.S.
   

UK total knee replacement market is projected to grow remarkably in the coming years.
 

• In the UK, the National Health Service (NHS) has introduced initiatives aimed at reducing long waiting lists for elective surgeries, including total knee replacements. This focus on reducing waiting times and improving patient access to surgery is helping drive the demand for TKRs in the UK.
   
• Additionally, the UK has seen an increase in knee replacements among younger, more active patients, driven by factors such as sports-related injuries and early onset osteoarthritis. Younger patients are opting for total knee replacement to maintain their mobility and active lifestyles, leading to a rising demand for knee replacement surgeries in the country.
   

Japan holds a dominant position in the Asia Pacific total knee replacement market.
 

• Japan has one of the fastest-aging populations in the world, with over 28% of its citizens aged 65 and older. As age is a major risk factor for knee joint degeneration and osteoarthritis, the aging population is driving the demand for total knee replacement surgeries in the country. Japan's aging demographic presents a significant market for total knee replacement procedures.
   
• Additionally, the Japanese government is actively investing in elderly healthcare, which includes coverage for joint replacement surgeries under the country’s universal healthcare system. This support has made total knee replacement surgeries more affordable and accessible, contributing to the market’s growth in Japan.
   

Total Knee Replacement Market Share

The market is characterized by the presence of several key players and a focus on services, technological innovation, and strategic partnerships. Leading companies are investing in advanced surgical tools and implant technologies to enhance the quality and efficiency of knee replacement procedures. Additionally, partnerships between healthcare providers, orthopedic clinics, and medical device manufacturers are increasing, driving innovation and expanding the adoption of knee replacement surgeries across various healthcare sectors. These collaborations are not only improving the availability and precision of surgical solutions but also fostering advancements in personalized implants and treatment protocols.
 

Total Knee Replacement Market Companies

Prominent players operating in the total knee replacement industry include:

• Amplitude Ortho (Amplitude Surgical)
• B Braun
• Corin Group
• Depuy Synthes (Johnson & Johnson)
• Enovis
• Exactech
• ODEV
• Medacta International
• Allegra Orthopaedics
• MicroPort Scientific Corporation
• restor3d
• Smith & Nephew
• Stryker Corporation
• Waldemar LINK
• Zimmer Biomet
   

Total Knee Replacement Industry News:

• In June 2024, DePuy Synthes received 510(k) FDA clearance for the clinical application of the VELYS Robotic-Assisted Solution in Unicompartmental Knee Arthroplasty (UKA). This approval is expected to increase the company’s reputation and its competitiveness in the market.
   
• In March 2023, Stryker announced the launch of Mako Total Knee 2.0, the next chapter in Mako SmartRobotics. Mako Total Knee 2.0 was designed to deliver trusted outcomes and provide great user experience. This launch increased the company’s product offering and enabled them with increased customer base.
   

The total knee replacement market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2021 – 2032 for the following segments:

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Market, By Product

• Primary knee replacement systems
• Partial knee replacement systems
• Revision knee replacement systems

Market, By Device Type

• Three-compartmental knee implants
• Bicompartmental knee implants
• Unicompartmental knee implants

Market, By Component

• Femoral
• Tibial
• Patellar

Market, By Implant Type

• Fixed-bearing implants
• Mobile-bearing implants
• Medial pivot implants
• Other implant types

Market, By Design

• Posterior stabilized design
• Cruciate retaining design
• Other designs

Market, By Surgery Type

• Traditional surgery type
• Technology assisted surgery type

Market, By Fixation Material

• Cemented
• Cementless
• Hybrid

Market, By Material

• Metal-on-plastic
• Ceramic-on-plastic
• Metal-on-metal
• Ceramic-on-ceramic

Market, By Polyethylene Inserts

• Antioxidant polyethylene inserts
• Highly cross-linked polyethylene inserts
• Conventional polyethylene inserts

Market, By End-use

• Hospitals
• Ambulatory surgical centers
• Other end-users.

The above information is provided for the following regions and countries:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Netherlands
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
• Middle East and Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East and Africa