Total Knee Replacement Market – By Product, By Device Type, By Component, By Implant Type, By Design, By Surgery Type, By Fixation Material, By Material, By Polyethylene Inserts, By End Use, & Global Forecast, 2024 – 2032

Total Knee Replacement Market Size

The global total knee replacement market size was valued at USD 9.4 billion in 2023 and is expected to exhibit growth at a CAGR of 5.1% from 2024 to 2032. The increase in cases of arthritis and osteoporosis, as well as the incidence of infections, is responsible for a boost in the number of knee revision surgeries performed, which consequently supports the growth of the market.
 

Increased life expectancy implies that an ever-increasing number of people will be suffering from these ailments, increasing the volume of total knee replacements done across the globe. The greater incidence of overweight population, which is a leading contributor to osteoarthritis, and the commonality of osteoporosis in patients suffering from rheumatoid arthritis increases the demand for total knee replacements. For instance, between the years 2019 and 2021, approximately 21.2% of adults in the U.S. (53.2 million) were reported to have arthritis diagnosed, as per the data provided by the CDC. Providing adequate attention to these patterns, along with the increasing prevalence of infections that result in knee revisions, should be a focus if we want to reduce the burden on healthcare systems and improve the existing public health measures and patient results.

Additionally, arthritis of the knee joint is one of the most debilitating conditions, resulting in pain, reduced mobility, and functional incapacity. A Total Knee Replacement or Total Knee Arthroplasty (TKA) is a surgical procedure beset with the hope of alleviating the symptoms. The aim is to restore mobility by replacing the damaged surfaces of the knee joint with artificial components.
 

Total Knee Replacement Market Trends

Technological progress has greatly helped to enhance market growth because of greater surgical accuracy, enhanced patient results, and satisfied patients.
 

• The VELYS Robotic-Assisted Solution, as well as other robotic systems, provides the capability to perform customized preoperative planning and intraoperative techniques. These systems produce three-dimensional replicas of the patient's knee. As a result, the surgeon can customize the method to the patient's specific anatomy and improve the accuracy of implant placement. Compared with the standard, these techniques are associated with smaller amounts of tissue injury and more rapid recovery.
   
• Furthermore, the evolution of intelligent implants, such as the Persona IQ implant, which has built-in sensors that track the activity level of the user, including motion and walking cadence, has emerged. These devices send this information to the healthcare provider, enabling them to keep track of recovery during the healing process and adjust rehabilitation accordingly. This helps improve user interaction and ultimately guarantees the best recovery results.
   
• Moreover, Patient-Specific Instrumentation (PSI) also brings development in personalized tools used in total knee arthroplasty by improving the design of the tools to meet patient needs. Improving the placement and alignment of an implant within the joint is the main goal of the technology. These advancements have a direct impact on surgery results and increase the number of patients who can receive knee replacements.
   

Total Knee Replacement Market Analysis

Based on product, the market is classified into primary knee replacement systems, partial knee replacement systems, and revision knee replacement systems. The primary knee replacement systems segment generated the highest revenue of USD 7.7 billion in 2023.
 

• Primary knee replacement systems are normally utilized in the first surgery or surgical procedure an individual undergoes. These surgeries include initial knee replacements and have greater numbers than revision or partial surgeries. This segment of the market is also the greatest because more people are treated for first-time total knee replacement surgeries as the prevalence of osteoarthritis and joint degenerative conditions increases.
   
• In addition, a larger segment of the market is also for primary knee replacement systems because these tools can be used by a wider group of patients with different ailments such as a severely destroyed knee joint due to arthritis, trauma, or degenerative diseases.
   

Based on device type, the total knee replacement market is categorized into three-compartmental knee implants, bicompartmental knee implants, and unicompartmental knee implants. The three-compartmental knee implants segment dominated the market by obtaining 77.4% of market shares in 2023.
 

• The three compartmental knee implants are used in total knee replacement surgery, which involves replacing all three compartments of the knee: medial, lateral, and patellofemoral. These surgeries are usually quite common, as they are performed for advanced or severely degenerated knees, such as arthritis which affects all compartments of the knee.
   
• Additionally, in comparison to uni or bicompartmental procedures, total knee replacements are more commonly performed, and for good reason. Patients who have suffered extensive damage to their knee joints are typically in need of a long-term solution, and this procedure provides one. Most patients presenting with severe arthritis or joint deterioration require full knee replacement, and that is the reason three compartmental implants are the most widely used.
   

Based on component, the total knee replacement market is classified into femoral, tibial, and patellar. The femoral segment is anticipated to generate the highest revenue of USD 7.3 billion during the forecast period.
 

• The femoral component is the most intricate aspect of a knee implant. It takes the form of the femur (thigh bone) to which it is attached, and it is also the most voluminous. Furthermore, it bears maximum load during physical activity. Hence, it needs engineering design that is precise and current in technology. For these reasons, the complexity of this component is promulgated by its expense and frequency of application.
   
• Furthermore, the femoral component is highly active in cocranking activities of the joint. It moves in conjunction with the tibial frequently and crudely. Most importantly, this component does so much work that it makes it most useful and also the most vital component in joint knee replacement surgery.
   

Based on implant type, the total knee replacement market is categorized into fixed-bearing implants, mobile-bearing implants, medial pivot implants, and other implant types. The fixed-bearing implants segment is anticipated to grow with the CAGR of 3.4% during forecast period.
 

• The ease of design and great resilience have made fixed-bearing implants the most popular type of implants in patients undergoing total knee replacement surgery. Additional simplicity during implantation has also raised its popularity. The fact that the polyethylene insert is firmly fixed to the tibial component of the implant indicates that most patients will achieve good long-term results.
   
• Moreover, fixed-bearing implants are also relatively cheaper than mobile-bearing or other advanced implants, thus are favored by both health providers and patients. Most of the surgeons trained have been trained around a fixed-bearing approach to surgery, which explains its higher prevalence.
   

Based on design, the total knee replacement market is classified into posterior stabilized design, cruciate retaining design, and other designs. The posterior stabilized design segment generated the highest revenue of USD 4.7 billion in 2023.
 

• The posterior stabilized design is mostly used for patients that have excessive damage to the knees or where the posterior cruciate ligament (PCL) is too badly damaged to preserve or where the design is to remove the PCL. This design is effective, and the enhanced stabilization prevents excessive anterior displacement of the tibia during knee flexion. This added stability makes it a popular choice.
   
• Also, the posterior stabilized design is more broadly applicable since, in a more wide range of patients, the PCL is not well functioning. This flexibility in applications combined with the predictable outcomes and confident performance of the PS implants has made it the best choice for numerous surgeons and patients, especially when it involves full knee replacement.
   

Based on surgery type, the total knee replacement market is categorized into traditional surgery type and technology assisted surgery type. The traditional surgery type segment dominated the market by obtaining 87% of market shares in 2023.
 

• Technological orthopedics has had a major development over the last few decades, but there continues to be a demand for traditional knee replacement surgery done without technological assistance.
   
• Compared to advanced surgical techniques, traditional surgery is often more cost-efficient. This benefit allows many surgical centers located in geographic areas with limited technological access to offer knee replacements.
   

Based on fixation material, the total knee replacement market is categorized into cemented, cementless, and hybrid. The cemented segment is anticipated to grow with the CAGR of 4.9% during the forecast period.
 

• The technique of cemented fixation has been used for many years and is favored by physicians for its proven effectiveness and long-term results. This technique relies on the use of bone cement to fix the implant to the bone, allowing for stabilization while providing immediate post-surgery recovery.
   
• Furthermore, cemented implants can be utilized with most patients, even older patients and those with weaker and less dense bones, which is often the case for patients with knee replacements. Its expectation is to work and its versatility make cemented fixation a favorable choice by most practitioners.
   

Based on material, the total knee replacement market is categorized into metal-on-plastic, ceramic-on-plastic, metal-on-metal, and ceramic-on-ceramic. The metal-on-plastic segment dominated the market by obtaining 59.2% of market share in 2023.
 

• The combination of metal and plastic has been investigated for a long time and has sufficient long-term clinical records that show its safety and efficacy. This material combination is the choice of most surgeons performing total knee replacement surgeries because of its low ability of joint movement limitations and low complications such as implant failure or wear over time.
   
• Moreover, compared to other types of charters, metal-on-plastic implants are found to be less complicated and have reduced risks of complications such as the release of metal ions or ceramic fractures. These can be a concern in the case of metal-on-metal or ceramic-based implants. The potential for post-surgical complications is reduced when combining a metal surface with a plastic insert.
   

Based on polyethylene inserts, the total knee replacement market is classified into antioxidant polyethylene inserts, highly cross-linked polyethylene inserts, and conventional polyethylene inserts. The antioxidant polyethylene inserts segment is anticipated to generate high revenue of USD 8.3 billion in forecast period.
 

• Antioxidant polyethylene inserts are enabled with stabilizers such as vitamin E that help in avoiding oxidation of the material. Antioxidant inserts are expected to have increased durability and would be highly desirable for surgeons aiming for long-lasting knee implants with lesser chances of revision surgeries.
   
• Further, antioxidant polyethylene has reduced the generation of wear particles leading to osteolysis and loosened the global market for medicine and health. This enhanced performance along with the ability to retain the material's mechanical strength over the long term has made antioxidant polyethylene especially preferred in younger and active patients needing implants.

Based on end-use, the total knee replacement market is segmented into hospitals, ambulatory surgical centers, and other end-users. The hospitals segment dominated the market in 2023 and is anticipated to reach USD 11.3 billion by the end of forecast period.
 

• It is anticipated that such comprehensive operations, such as total knee prosthesis, will be performed at hospitals, which normally have all the required facilities and have trained orthopedic surgeons. Moreover, they are able to deal with any complications and provide extensive post-operative services, such as rehabilitation. This explains why they are preferred by patients and healthcare providers.
   
• Furthermore, hospitals, especially big multi-specialty corporations, deal with patients that have other more complicated medical issues and so cannot undergo outpatient surgeries. This ability to take on complex cases and provide inpatient care makes hospitals the major end-use for total knee replacement procedures.

North America total knee replacement market accounted for USD 5.1 billion market revenue in 2023 and is anticipated to grow at a CAGR of 3.8% between 2024 – 2032 period.
 

• In North America, Osteoarthritis is widespread especially with older people which makes the rate of total knee replacement surgery very high. Since the population is less active and struggles with obesity, the rates of osteoarthritis are way higher than other places which require knee replacements.
   
• Also, in the U.S. region, there is also a high demand in the market for help with joint robotics and tailor-made surgical knee parts. The ability to self-perform more meticulous and tailored procedures leads to beneficial results and allows patients to recover rapidly. These factors positively affect the market's growth for total knee replacement procedures in the U.S.
   

U.S. total knee replacement market accounted for USD 4.8 billion market revenue in 2023 and is estimated to hold substantial share between 2024 – 2032 period.
 

• A growing elderly population in the U.S. can be anticipated during the mentioned timeframe above so the need for greater joint assistance will rise as well. This shift in population demographics explains the increase in total knee replacements in the US where Osteoarthritis is widespread.
   
• Additionally, the replacement of knees is proliferating for several reasons, including increased accessibility as the U.S. healthcare policy permits ample coverage of joint replacements through both Medicare and private health insurance, which aids a large fraction of the populace who seek coverage. This factor in addition to greater cognizance and the early stage diagnosis of joint problems is fueling the increase of the market in the US.
   

UK total knee replacement market is projected to grow remarkably in the coming years.
 

• In the UK, the recent steps taken by the National Health Service (NHS) to tackle the long waiting lists for planned surgeries, including knee replacements, is also helping to increase the availability of TKRs in the UK. The reduction in waiting time and improved patient access to surgery is what makes the TKRs more in demand in UK.
   
• In addition, in the UK, younger and more active people with sporting injuries, as well as early osteoarthritis, are driving the increase in knee replacements. Younger patients are seeking joint replacements to facilitate their active lifestyle. As such, the demand for knee replacement operations is rising in the country.
   

Japan holds a dominant position in the Asia Pacific total knee replacement market.
 

• Japan is one of the countries with a very high percentage of its population over 65, which exceeds 28%, causing it to have one of the fastest aging populations in the world. This means that there is a high demand for knee replacement surgeries in the country as age and high knee joint degeneration along with osteoarthritis are common issues in older people. Thus, it contributes to the market in Japan.
   
• In addition, there is significant government spending towards elderly illnesses; healthcare covers joint replacement surgeries due to the country's universal healthcare system. This makes total knee replacement surgeries economical and easily accessible, which has helped in growing the market in Japan.
   

Total Knee Replacement Market Share

The market is a competitive arena with numerous major companies and emphasis on service and innovation as well as business collaboration. Major players are focusing on the development of implants and surgical instruments to improve the performance of knee replacement surgeries. At the same time, collaboration between providers of such services as orthopedic surgery, practitioners of medicine, and developers of surgical instruments is growing, which increases the creativity and broadens the use of knee joint prosthetics in different medical businesses. Not only are these alliances enhancing the access and accuracy of surgical techniques, but they are also improving the design of custom implants and the methods of treatment.
 

Total Knee Replacement Market Companies

Prominent players operating in the total knee replacement industry include:

• Amplitude Ortho (Amplitude Surgical)
• B Braun
• Corin Group
• Depuy Synthes (Johnson & Johnson)
• Enovis
• Exactech
• ODEV
• Medacta International
• Allegra Orthopaedics
• MicroPort Scientific Corporation
• restor3d
• Smith & Nephew
• Stryker Corporation
• Waldemar LINK
• Zimmer Biomet
   

USPs for Top Players:

• DePuy Synthes (Johnson & Johnson) supplies sophisticated knee replacement systems with tailored options that enhance mobility and patient outcomes.
   
• Zimmer Biomet brings forward new knee implants built with machine engineered designs that provide strength and facilitate natural movement. 
   
• Smith & Nephew concentrates on new methods of performing knee replacement procedures that are less invasive, thereby improving recovery and patient experience.
   

Total Knee Replacement Industry News:

• In June 2024, DePuy Synthes received 510(k) FDA clearance for the clinical application of the VELYS Robotic-Assisted Solution in Unicompartmental Knee Arthroplasty (UKA). This approval is expected to increase the company’s reputation and its competitiveness in the market.
   
• In March 2023, Stryker announced the launch of Mako Total Knee 2.0, the next chapter in Mako SmartRobotics. Mako Total Knee 2.0 was designed to deliver trusted outcomes and provide great user experience. This launch increased the company’s product offering and enabled them with increased customer base.
   

The total knee replacement market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2021 – 2032 for the following segments:

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Market, By Product

• Primary knee replacement systems
• Partial knee replacement systems
• Revision knee replacement systems

Market, By Device Type

• Three-compartmental knee implants
• Bicompartmental knee implants
• Unicompartmental knee implants

Market, By Component

• Femoral
• Tibial
• Patellar

Market, By Implant Type

• Fixed-bearing Implants
• Mobile-bearing Implants
• Medial pivot implants
• Other implant types

Market, By Design

• Posterior stabilized design
• Cruciate retaining design
• Other designs

Market, By Surgery Type

• Traditional surgery type
• Technology assisted surgery type

Market, By Fixation Material

• Cemented
• Cementless
• Hybrid

Market, By Material

• Metal-on-plastic
• Ceramic-on-plastic
• Metal-on-metal
• Ceramic-on-ceramic

Market, By Polyethylene Inserts

• Antioxidant polyethylene inserts
• Highly cross-linked polyethylene inserts
• Conventional polyethylene inserts

Market, By End Use

• Hospitals
• Ambulatory surgical centers
• Other end-users

The above information is provided for the following regions and countries:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Netherlands
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
• Middle East and Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East and Africa