Pulmonary Arterial Hypertension Market Analysis

Pulmonary Arterial Hypertension Market Analysis

The endothelin receptor antagonist segment is predicted to witness 5.5% growth rate through 2027 owing to the rising demand for endothelin receptor antagonist drugs. These drugs are widely recommended as a targeted therapy to reverse the damage of the heart & lungs, slow the progression of PAH, and dilate blood vessels among others. The clinical studies have confirmed that patient with pulmonary arterial hypertension produces high amount of endothelin that often leads to high blood pressure. Thus, an endothelin receptor antagonist is highly prescribed by physicians to reduce the amount of endothelin present in the blood vessels. Moreover, progressive investments for research and development of endothelin receptor antagonist will promote the segment growth. Recently there has been a rapid expansion in research targeting endothelin receptor that has other therapeutic advantages, mainly in the treatment of pulmonary arterial hypertension.

The oral segment in the pulmonary arterial hypertension market dominated more than 69% of the revenue share in 2020 led by the oral route of administration that offers a broad range of dosage forms such as tablets, capsules, and solutions among others. The oral route is the most preferred route for drug administration attributed to its benefits including the convenience of drug administration, patient compliance, and non-invasiveness. Oral therapies increase patient safety and comfort at an affordable cost. Furthermore, rapid delivery of drugs, a higher rate of bioavailability, and high efficacy among others will propel the segment revenue.
 

U.S. dominated the North America pulmonary arterial hypertension market and will reach USD 6.25 billion by 2027 driven by the numerous factors such as the availability of a high number of board-certified physicians, growing hospital admissions related to PAH, and growing supportive government initiatives among others. The prevalence of PAH is increasing in the country attributed to the risk factors comprising smoking, HIV, sedentary lifestyle, and alcohol consumption among others. In addition, in the U.S., the Orphan Drug Act (ODA) was introduced in 1983 to provide incentives for industry investment in treatments for PAH.
 

In Europe, Germany market held 10% of revenue share in 2020 and is predicted to cross USD 194 million by 2027 on account of the increase in the prevalence of pulmonary arterial hypertension, optimal health workforce, and facilitative government initiatives to improve the health of patients suffering from PAH in the country. As per the article published by the National Center for Biotechnology Information, in 2016, left heart disease is one of the common factors causing PAH that affected around 1.3 million people in Germany. According to the article published in 2020, over 5.6 million health workers were working in Germany. A large health workforce highlights well-developed healthcare infrastructure in the country. The German health care system covers over 80% of the medical costs of its residents is assisting the patients to avail the quality of treatment for pulmonary arterial hypertension.