Isothermal Nucleic Acid Amplification Technology Market Size

Isothermal Nucleic Acid Amplification Technology Market Size

Isothermal Nucleic Acid Amplification Technology Market size surpassed USD 1.3 billion in 2021 and is expected to witness an 11.8% CAGR from 2022 to 2028 due to technological developments, surging ageing population, and foreign financing for R&D. Additionally, rising demand for point-of-care (PoC) testing and growing demand for quick diagnostics will add to market expansion.

COVID-19 pandemic positively impacted isothermal nucleic acid amplification technology (INAAT) market. Since INAAT offers simple operation, rapid detection, and accurate results. As a result, it becomes more ideal for primary testing centers in urban as well as rural areas. INAAT is in high demand since PCR-based nucleic acid detection technology is time-consuming and requires specialist equipment.

Moreover, it is difficult to work with PCR in primary-level medical institutions. Antibody-based detection has limitations because of the late appearance of antibodies, that makes early diagnosis of virus difficult, whereas antigen-based detection has low sensitivity, that often result a high false-negative rate.

Isothermal nucleic acid amplification technology (INAAT) methods allow for the rapid, exponential detection of a nucleic acid target sequence. This process is not limited by the constraint of thermal cycling. Isothermal amplification, when integrated into microsystems or portable devices, improves nucleic acid-based on-site diagnostics and increases sensitivity. In addition, using different enzymatic approaches to separate the two DNA strands prior to replication, INAAT can achieve amplification in 15-16 minutes.