Hyaluronic Acid Market – By Product (Single Injection Dose, Multiple Injection Dose), Application (Dermal Fillers, Osteoarthritis, Ophthalmic, Vesicoureteral Reflux), Grade (Cosmetic, Pharmaceutical), End-use (Hospitals, ASC) – Global Forecast 2024 – 2032

Hyaluronic Acid Market Size

Hyaluronic Acid Market size was valued at around USD 9.8 billion in 2023 and is estimated to grow at a CAGR of 7.2% between 2024 and 2032. This robust market growth can be attributed to various factors, including continuous advancements in skincare technology, rising demand for cosmetic implants procedures, growing aging population and, increasing prevalence of chronic diseases and conditions, among other contributing factors.
 

Moreover, chronic diseases such as osteoarthritis, diabetes, and cardiovascular diseases are common across the world. Medical therapies involving hyaluronic acid include viscosupplementation for osteoarthritis patients and wound healing for diabetic ulcers. The growth in chronic diseases needs therapeutic measures, resulting in increased demand for hyaluronic acid-based medicinal products.
 

For instance, according to the Centers for Disease Control and Prevention, 1 in 5 individuals in the U.S. (53.2 million) is affected by arthritis. Although there are over 100 various types of arthritis, osteoarthritis (OA) is the most common, affecting 32.5 million U.S. individuals.
 

Furthermore, advances in biotechnology and manufacturing processes have enabled the production of high-quality, pure, and standardized hyaluronic acid. These advancements have reduced production costs, improved scalability, and enhanced the consistency of hyaluronic acid products, making them more accessible and affordable for manufacturers and consumers alike, thereby contributing to the market progress.
 

Hyaluronic acid is a naturally occurring polysaccharide found in the human body and many other organisms. It belongs to the glycosaminoglycan family and is composed of repeating units of disaccharides, specifically glucuronic acid and N-acetylglucosamine. Hyaluronic acid is a key component of connective tissues, synovial fluid, and skin, where it plays important roles in hydration, lubrication, and tissue integrity.
 

Hyaluronic Acid Market Trends

The market is experiencing several notable trends that are shaping its growth and development. Factors such as rise in anti-aging treatments, expansion of cosmetic applications, surging demand for combination therapies, and continuous advancements in novel drug delivery systems and formulation technologies, among other factors are propelling the industry growth.
 

• Further, there is a growing consumer awareness and demand for natural, organic, and sustainable skincare products. Manufacturers are responding to this trend by sourcing high-quality, eco-friendly ingredients and adopting environmentally conscious practices in HA production and formulation. Non-animal-derived HA sources, green manufacturing processes, and biodegradable packaging align with consumer preferences for ethical and sustainable beauty products.
   
• Moreover, combination therapies involving HA with other cosmetic ingredients such as vitamins, peptides, antioxidants, and growth factors are gaining popularity. These synergistic formulations offer comprehensive skincare benefits, including hydration, firming, brightening, and collagen stimulation. The trend towards personalized skincare regimens and multifunctional products drives the development of HA-based combinations tailored to address specific skin concerns and preferences.
   

Hyaluronic Acid Market Analysis

The market by product is categorized into multiple injection dose, and single injection dose. The multiple injection dose segment garnered USD 6.5 billion revenue in 2023.
 

• Multiple injection doses of hyaluronic acid are often used in treatments such as dermal fillers and viscosupplementation for osteoarthritis. Compared to single injections, multiple doses provide more sustained and longer-lasting effects. By administering hyaluronic acid in a series of injections over a prescribed period, healthcare providers can achieve gradual and cumulative improvements in skin texture, volume restoration, joint lubrication, and pain relief.
   
• In addition, it allows healthcare providers to tailor treatment plans according to individual patient needs, goals, and response to therapy. Patients with severe or advanced signs of aging, joint degeneration, or volumetric deficits may benefit from a series of injections spaced over several weeks or months to achieve optimal outcomes. Tailored treatment plans enable personalized care and address specific concerns while minimizing potential adverse reactions and maximizing patient satisfaction.
  
   

Based on application, the hyaluronic acid market is segmented into dermal fillers, osteoarthritis, ophthalmic, vesicoureteral reflux, and other applications. The dermal fillers segment accounted for over 40% business share in 2023 and is anticipated to witness significant growth during the forecast period.
 

• Dermal fillers offer a non-surgical alternative to invasive cosmetic procedures such as facelifts and implants. They are injected directly into the skin to address volume loss, fine lines, and wrinkles, providing immediate results without the need for incisions or downtime. The non-surgical nature of dermal filler treatments appeals to individuals seeking cosmetic enhancements with minimal risk and recovery time.
   
• Moreover, HA-based dermal fillers offer versatility in treating various facial areas and aesthetic concerns. They can be used to augment lips, sculpt cheekbones, fill in under-eye hollows, smooth nasolabial folds, and enhance jawlines. The ability to customize treatment plans and target specific facial features allows healthcare providers to address individual patient needs, preferences, and aesthetic goals, driving demand for HA fillers across diverse patient demographics.
   

Based on grade, the hyaluronic acid market is segmented into cosmetic grade hyaluronic acid and pharmaceutical grade hyaluronic acid. The cosmetic grade hyaluronic acid segment accounted for around 68.6% business share in 2023.
 

• HA is known for its anti-aging properties, including plumping and firming the skin, reducing the appearance of fine lines and wrinkles, and promoting a more youthful complexion. Cosmetic-grade HA formulations deliver these anti-aging benefits by restoring volume, improving skin texture, and enhancing overall skin tone and elasticity. As consumers seek effective solutions to combat signs of aging, the demand for HA-based anti-aging products remains high.
   
• Additionally, the popularity of minimally invasive cosmetic procedures, such as injectable dermal fillers and mesotherapy, has surged in recent years. Cosmetic-grade HA is a key component in dermal fillers used for facial contouring, lip augmentation, and wrinkle reduction. Its biocompatibility, pliability, and ability to integrate seamlessly into the skin make it an ideal filler material for restoring volume and enhancing facial aesthetics.
   

The hyaluronic acid market by end-use is categorized into hospitals, dermatology clinics, ambulatory surgical centers, and other end-users. The hospitals segment accounted for around USD 5.7 billion revenue size in 2023.
 

• Hospitals invest in advanced orthopedic technologies, surgical techniques, and therapeutic modalities to optimize patient outcomes and enhance clinical efficiency. HA viscosupplementation is integrated into comprehensive orthopedic care pathways, offering patients a conservative treatment option that complements other modalities such as physical therapy, bracing, and medication management. Hospitals leverage HA injections as part of multimodal pain management strategies and joint preservation protocols for improved patient care and satisfaction.
   
• Additionally, many patients prefer non-surgical treatment options for musculoskeletal conditions like osteoarthritis, particularly those aimed at pain relief and functional improvement. HA injections offer a non-surgical alternative to joint replacement surgery, providing symptomatic relief and enhancing quality of life for patients with mild to moderate osteoarthritis. Hospitals cater to patient preferences by offering HA viscosupplementation as part of comprehensive orthopedic care and pain management programs.
   

North America hyaluronic acid market accounted for USD 4.2 billion revenue in 2023 and is predicted to witness substantial market growth.
 

• North America has a sizable aging population, with a growing number of individuals aged 65 and above. As people age, the natural production of HA in the body decreases, leading to skin aging, joint stiffness, and other age-related issues. The rising aging population drives the demand for HA-based products and treatments to address age-related concerns such as wrinkles, sagging skin, and osteoarthritis.
   
• Furthermore, North America is at the forefront of skincare research, development, and innovation. The region witnesses continuous advancements in skincare technologies, formulations, and delivery systems, including HA-based serums, moisturizers, and masks. Technological innovations enhance the efficacy, safety, and user experience of HA skincare products, driving consumer adoption and market expansion, leading to the regional growth.
   

Hyaluronic Acid Market Share

The hyaluronic acid industry is competitive in nature, with several large multinationals and small and mid-sized companies competing in the industry. The development and launch of novel advanced products based on different technologies is among a key market strategy. Some of the leading industry players including Allergan, Inc., Anika Therapeutics, Inc., F. Hoffmann-La Roche Ltd, Sanofi, Zimmer Biomet, among others have a notable presence in the market.
 

Hyaluronic Acid Market Companies

Some of the eminent market participants operating in the hyaluronic acid industry include:

• Allergan, Inc.
• Anika Therapeutics, Inc.
• Bloomage Biotech Co., Ltd
• F. Hoffmann-La Roche Ltd
• Ferring B.V.
• GALDERMA
• LG Chem, Ltd.
• Lifecore Biomedical, Inc.
• Salix Pharmaceuticals, Ltd.
• Sanofi
• Seikagaku Corporation
• Zimmer Biomet
   

Hyaluronic Acid Industry News

• In June 2023, Galderma announced that the U.S. Food and Drug Administration (FDA) granted approval for Restylane Eyelight for the treatment of undereye hollows, commonly known as dark shadows, in individuals over the age of 21. It is an undereye hyaluronic acid (HA) dermal filler that treats volume loss under the eyes and provides patients with natural-looking results.
   
• In May 2023, Allergan Aesthetics, an AbbVie company, has received FDA clearance for Skinvive by Juvéderm, which was marketed as the "first and only" hyaluronic acid intradermal microdroplet injection for skin smoothness available in the U.S.
   

Hyaluronic acid market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 – 2032 for the following segments:

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Market, By Product

• Multiple injection dose
• Single injection dose

Market, By Application

• Dermal fillers
• Osteoarthritis
• Ophthalmic
• Vesicoureteral reflux
• Other applications

Market, By Grade

• Cosmetic grade hyaluronic acid
• Pharmaceutical grade hyaluronic acid

Market, By End-use

• Hospitals
• Dermatology clinics
• Ambulatory surgical centers
• Other end-users

The above information is provided for the following regions and countries:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
• Middle East and Africa
  • Saudi Arabia
  • South Africa
  • UAE
  • Rest of Middle East and Africa