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Transthyretin Amyloidosis Treatment Market size was valued at USD 5.9 billion in 2023 and is expected to reach USD 11.2 billion by 2032, growing at a CAGR of 7.5% over the analysis period. Increasing prevalence of transthyretin amyloidosis, a rare genetic disorder, coupled with advancements in treatment options for rare diseases are fuelling market expansion.
Additionally, as the disease is more common in older individuals, rising aging population, particularly in developed countries, is contributing to market growth. For instance, wild-type transthyretin amyloidosis (ATTRwt) mainly affects older men, and certain autopsy studies have shown that 25% of patients aged above 80 years old have transthyretin amyloid myocardial deposits. Thus, as the global geriatric population rises, the incidence rates of transthyretin amyloidosis disease are expected to increase, thereby fostering the market growth.
Transthyretin amyloidosis (ATTR) treatment refers to the medical interventions aimed at managing and slowing the progression of ATTR amyloidosis, a rare, progressive, and often fatal disease caused by the buildup of abnormal transthyretin protein in tissues and organs. Treatment approaches include medications to stabilize or reduce the production of transthyretin and supportive therapies to manage symptoms and complications.
Some of the top transthyretin amyloidosis treatment companies are Acrotech Biopharma, LLC, AstraZeneca PLC, Astellas Pharma Inc., BridgeBio Pharma, Inc., Bristol-Myers Squibb Company, Ionis Pharmaceuticals, Inc., Johnson & Johnson, Prothena Biosciences Limited, Pfizer Inc., SOM Innovation Biotech, S.L.
North America accounted 37.6% revenue share of the transthyretin amyloidosis treatment industry in 2023 and is set to expand at a considerable growth rate through 2032 due to well-established healthcare infrastructure, and high awareness about rare diseases among healthcare professionals and patients.
The ATTR-CM segment generated USD 4.7 billion in revenue in 2023 and is estimated to grow at a notable CAGR from 2024-2032 owing to the rising advancements in diagnostics techniques that aid in timely intervention.
Transthyretin amyloidosis treatment industry was valued at USD 5.9 billion in 2023 and is poised to expand at 7.5% CAGR between 2024 and 2032 owing to the increasing prevalence of transthyretin amyloidosis, a rare genetic disorder, coupled with advancements in treatment options for rare diseases.