Nucleotides Market Analysis

Based on nitrogenous base, the global market is segmented into purine and pyrimidine. The purines segment accounted for majority of buiness share in 2022.

• Purine derivatives are often used in pharmaceuticals and therapeutic applications. For example, purine-based drugs may be used to treat conditions such as gout multiple sclerosis, as well as certain cancers and viral infections.
  
• Similarly, purines are widely used in molecular biology research, genetic engineering, and biotechnology. They serve as building blocks for DNA synthesis in various applications, including PCR (polymerase chain reaction) and DNA sequencing.
  
• Therefore, the increasing demand for nucleotides in the pharmaceutical industry as well as in research application may contribute to a higher market share for purines segment.
  

Based on application, the nucleotides market is classified into diagnostics research, pharmaceuticals, and other applications. In 2022, diagnostics research segment dominated the market and was valued at USD 382.4 million.

• Nucleotides play a fundamental role in numerous molecular diagnostics techniques, facilitating precise detection, analysis, and comprehension of genetic material across diverse diagnostic applications. Also, ongoing advancements in nucleotide-based technologies persistently propel the utilization of these technologies in the domain of diagnostics research. Thus, with a rising need for precise and sensitive diagnostics, it is anticipated that the market for nucleotides employed in diagnostic applications will experience significant growth.
  

Based on technology, the nucleotides market is categorized into TaqMan allelic discrimination, SNP by pyrosequencing, gene chips & microarrays, and other technologies. The TaqMan allelic discrimination segment is anticipated to grow at 5.9% between 2023 to 2032 period.

• TaqMan allelic discrimination assays is a real-time PCR-based method known for their high accuracy and sensitivity. In this technology, nucleotides are used as part of the PCR reaction mix. These nucleotides are incorporated into the growing DNA chain by a DNA polymerase during the extension step.
  
• TaqMan allelic discrimination is versatile and can be applied to various research areas, including human genetics, pharmacogenomics, and infectious disease research. Its broad applicability across different fields contributes to its widespread adoption.
  

Based on product, the nucleotides market is divided into deoxynucleotides, ribonucleotides, labelled nucleotides, and dideoxy nucleotides. The deoxynucleotides segment held is expected to reach USD 527.6 million by 2032.

• Deoxynucleotides are essential building blocks for DNA synthesis. They serve as the monomeric units that polymerize to form the DNA backbone during replication. Thus, increasing need for accurate and efficient DNA synthesis propels the growth of this segment.
  
• Deoxynucleotides are critical in DNA replication and amplification processes. Techniques like polymerase chain reaction (PCR), a widely used method in molecular biology, rely on deoxynucleotides for the amplification of specific DNA sequences. Thus, increasing utilization of deoxynucleotides is expected to augment the segment expansion.
  

The North America nucleotides market is anticipated to witness growth at 5.5% during the analysis period to reach USD 420.2 million by 2032.

• North America, particularly the U.S., is epicenter to few of the world's leading biotechnology and pharmaceutical companies. The region has a robust research and development infrastructure, which contributes to the demand for nucleotides in various applications, including drug development, diagnostics, and genetic research.
  
• Also, the region has well-established healthcare systems and is often an early adopter of advanced diagnostic technologies. Therefore, adoption of nucleotides in molecular diagnostics, and the region's emphasis on cutting-edge healthcare solutions contributes to a higher market share for nucleotides.