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Advancements in organ preservation technologies, including machine perfusion and cryopreservation methods, enhance the viability and quality of xenogeneic organs.Similarly, advances in genetic engineering techniques, such as CRISPR-Cas9 allows healthcare professionals to modify animal genomes to create genetically engineered pigs or other animals with organs that are more compatible with human recipients. Further, increasing adoption of robotics in minimally invasive surgical techniques will provide potential to improve the precision and safety of xenotransplantation procedures. Robotic-assisted surgery can enhance surgical outcomes and reduce post-operative complications.