Primary Cell Culture Market

Primary Cell Culture Market Size

Primary Cell Culture Market size was valued at around USD 5 billion in 2023 and is estimated to grow at 12.2% CAGR from 2024 to 2032. The market experienced significant growth driven by the increasing prevalence of chronic diseases such as cancer, infections, autoimmune disorders, diabetes mellitus, cardiovascular diseases, and nephrological conditions.

According to the latest estimates from the International Agency for Research on Cancer (IARC) in 2022, there were approximately 20 million new cancer cases projecting a rise of over 35 million new cancer cases by 2050, reflecting a substantial 77% increase from the estimated cases in 2022. This upward trend in cancer incidence globally is expected to drive demand for new therapeutics and personalized medicines. Therefore, as researchers strive to develop tailored treatments for such diseases, primary cell culture techniques become essential for modeling patient-specific responses and understanding disease mechanisms at the cellular level. This need for precision in drug discovery and development fuels the adoption of primary cell culture methodologies, thereby boosting market growth.

Primary cell culture involves the propagation of cells directly isolated from living tissues, including diverse cell types including human or animal cells. Cultured in specialized media, these cells require precise environmental conditions, including nutrients, growth factors, and supplements tailored to their specific requirements. The cell culture media compositions vary widely, providing essential nutrients, pH buffering, and growth-promoting factors crucial for cell survival, proliferation, and functionality, facilitating various biomedical and biotechnological research applications.

Primary Cell Culture Market Trends

Increasing funding for cell-based research is poised to propel market growth. The funding enables researchers to explore novel therapeutic approaches, develop innovative technologies, and conduct comprehensive preclinical studies, thereby driving the demand for primary cell culture products.

• For instance, in October 2023, the California Institute of Regenerative Medicine (CIRM) granted USD 2 million to the Keck School of Medicine of USC to enhance its recently inaugurated cGMP Laboratory. This advanced facility aimed to expedite early-stage research into clinically viable cell and gene therapies, facilitating their transition from laboratory settings to clinical applications through integrated advanced technologies for product development and testing.
  

Thus, constant support from government along with collaborative approach between government and academic institute to develop novel therapies will spur the market growth during the analysis period.

Primary Cell Culture Market Analysis

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Based on cell type, the market is classified into animal cells and human cells. The animal cells segment is anticipated to acquire the largest market share and sustain its dominance to reach USD 8 billion by 2032.

• The expansion of animal-origin primary cell applications in vaccine development significantly drives segment growth. Extensively researched and characterized animal cells such as mice, rats, and porcine cells serve as invaluable tools across various research areas, including human biology, disease mechanisms, drug development, and toxicity testing.
  
• Also, the comprehensive product offerings from companies contribute to segment growth.
  

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Based on components, the primary cell culture market is categorized into products, media, and reagents and supplements. The reagents and supplements segment is projected to hold the largest market share of 41.4% in 2023 and is expected to maintain dominance throughout the analysis period.

• The dominance of the reagents and supplements segment stems from their increasingly routine utilization in both research and manufacturing involving primary cell culture. Also, reagents such as growth factors, sera, and buffers establish an environment mirroring for the survival and proliferation of primary cells.
  
• Thus, the availability of diverse, high-quality reagents and supplements tailored to specific cell types and research purposes further solidified their prominence in the market, as researchers rely on these products to ensure the success and reproducibility of their experiments and outcomes.
  

Based on application, the primary cell culture market is classified into drug screening and toxicity testing, vaccine production, cell & gene therapy development, regenerative medicine, and other applications. The cell & gene therapy development segment accounted for USD 1.7 billion in 2023 and is expected to capture USD 4.7 billion market revenue by 2032.

• The cell and gene therapies exhibit promising potential in treating a spectrum of diseases, spanning from cancer to genetic disorders and autoimmune conditions.  Also, the therapy involves the manipulation and alteration of cells or genes to restore or augment their functionality.
  
• Further, availability of numerous products in pipeline will augment the market growth. For instance, according to the In-vivo Citeline Commercial report released in January 2023, anticipated approval of 13 new gene therapies in the U.S. and Europe by year-end underscores the substantial market demand for gene-based treatments. Thus, the field of primary cell culture, which serves as a crucial platform for drug discovery, toxicity testing, and regenerative medicine research, is expected to experience significant expansion.
  

Based on the end-user, the primary cell culture market is categorized into pharmaceutical and biotechnology companies, research institutes and academic laboratories, contract research organizations (CROs), and other end-users. The pharmaceutical and biotechnology companies segment accounted for the largest revenue share in the market and is expected to account for USD 4.9 million by 2032.

• Increasing R&D investments by pharmaceutical and biotechnology companies to innovate and development of new therapeutic products. The culture enable drug candidate screening, biologics production for preclinical and clinical trials, and the optimization of manufacturing processes. Thus, indicates the essential role of cell cultures in the R&D process.
  
• Moreover, the soaring significance of primary cell culture in cultivating patient-derived cells and tissues for applications such as cell therapy and regenerative medicine is driving significant investments from biopharmaceutical companies.
  

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U.S. dominated the North American primary cell culture market accounting for the highest market share 90.5% in 2023 anticipating significant growth over the analysis period.

• The region benefits from well-established regulatory frameworks supporting biopharmaceutical innovation. Also, the country holds numerous academic and research institutions at the forefront of primary cell culture advancements, further solidifying its leading position in the market.
  
• Further, the presence of leading pharmaceutical and biotechnology companies drives significant demand for primary cell culture products.
  

Germany exhibited a high growth potential in the European primary cell culture market.

• Germany's market is buoyed by its renowned biotechnology sector, characterized by a robust ecosystem of research institutions, biotech companies, and academic centers.
  
• The country's strong emphasis on R&D, coupled with favorable government policies supporting biotech innovation, propels the market growth.
  
• Furthermore, Germany's strategic location in Europe facilitates collaborations and market access across the continent, thereby augmenting its position in the global market.
  

The Asia Pacific primary cell culture market is expected to exhibit the fastest growth over the forecast period.

• Asia Pacific has experienced significant growth in the market with a CAGR of 12.7%. The region boasts significant pharmaceutical expenditures, with China and Japan ranking among the top five pharmaceutical markets globally.
  
• Further, due to transformative potential of cell and gene therapies in patient care, numerous local companies are actively engaged in advancing technologies including cell and gene therapies and improving their accessibility across the APAC region, thereby expanding opportunities in the market.
  

Japan holds prominent position in the Asia Pacific primary cell culture market.

• The country boasts advanced healthcare infrastructure, robust regulatory frameworks, and significant investments in biotechnology and life sciences domain.
  
• Also, leading pharmaceutical and biotech companies drive market growth through their focus on R&D and the development of novel therapeutic approaches.
  
• The market is further propelled by collaborations between academia, industry, and government organizations to accelerate the translation of research findings into clinical applications. Such aforementioned factors are expected to supplement the country level market growth.
  

Primary Cell Culture Market Share

The market hosts numerous companies competing for market share. Market share can be influenced by factors such as technological advancements, product innovation, strategic partnerships and collaborations, mergers and acquisitions, and changes in customer preferences. Companies that invest in developing innovative cell culture products and solutions tailored to specific research needs and applications may gain a competitive edge.

Primary Cell Culture Market Companies

Some of the prominent players operating in the primary cell culture industry include:

• BioLamina AB
• Corning Incorporated
• Creative Bioarray
• Cyagen
• FUJIFILM Wako Pure Chemical Corporation
• Kosheeka
• Lifeline Cell Technology
• Lonza Bioscience
• Merck KGaA
• PELOBIOTECH GmbH
• PromoCell GmbH
• STEMCELL Technologies
• Thermo Fisher Scientific Inc.
  

Primary Cell Culture Industry News:

• In March 2023, Nucleus Biologics and Stoic Bio established a supply agreement with the Center for Breakthrough Medicines (CBM), designating Nucleus Biologics as the primary supplier of cell culture media and essential biological solutions. The collaborative endeavor is geared towards expediting the development and delivery of top-tier therapies to the market.
  
• In March 2023, iXCells Biotechnologies USA, Inc. partnered with Fujifilm WAKO Pure Chemical Corp. under a distribution agreement. This collaboration expands their portfolio, offering a range of primary cell types and associated culture media and supplements to Japan's drug discovery researchers, aiming to diversify market offerings.
  

The primary cell culture market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2021 – 2032 for the following segments:

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Market, By Cell Type

• Animal cells
• Human cells

Market, By Component

• Products
  • Blood cell
  • Nerve cell
  • Bone marrow
  • Endothelial cell
  • Skin cell
  • Muscle cell
  • Other cell types
• Media
• Reagents & supplements
  • Cell dissociation and cell attachment solutions
  • Buffers and salts
  • Cell freezing media
  • Sera, growth factors & cytokines
  • Other reagents & supplements

Market, By Application

• Drug screening and toxicity testing
• Vaccine production
• Cell & gene therapy development
• Regenerative medicine
• Other applications

Market, By End-user

• Pharmaceutical and biotechnology companies
• Research institutes and academic laboratories
• Contract research organizations (CROs)
• Other end-users

The above information is provided for the following regions and countries:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Netherlands
  • Rest of Europe
• Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East and Africa
  • Saudi Arabia
  • South Africa
  • UAE
  • Rest of Middle East and Africa