Polyglycerol Sebacate (PGS) Market Size - By Form, By Application, Forecast, 2024-2032

Polyglycerol Sebacate Market Size

The global polyglycerol sebacate market size was valued at USD 65.49 million in 2023 and is anticipated to grow at 10.6% CAGR from 2024 to 2032. Polyglycerol sebacate is a biocompatible and biodegradable polymer resin formed by polycondensation of sebacic acid (from castor oil) and glycerol. PGS is used as an elastomer in coating of bio textiles such as valves, meshes made up of polyethylene, polyester among others. It is most widely used in tissue engineering, especially for nerve and cardiovascular tissue regeneration applications.
 

It can also be extruded with some additives which can be used as a bone graft in joint replacement applications. Although the current market of PGS is very negligible and is under development phase, there exists a huge potential to replace other biomaterials such as polylactic acid, poly-L-lactic acid (PLLA), poly glycolic acid (PG), polycaprolactone (PCL) in future as PGS can mimic natural tissue in terms of flexibility. Also, it is soft in nature, robust and has low cost as compared to other biodegradable elastomers. Current applications of PGS elastomer include nerve guidance, tissue regeneration, blood vessel reconstruction, drug delivery among others.
 

The increasing demand for tissue engineering and regenerative medicine is driving significant interest in advanced biomaterials, including polyglycerol sebacate (PGS). PGS, known for its biocompatibility and customizable properties, is emerging as a key material in creating scaffolds and matrices for tissue regeneration. Its unique degradability and mechanical properties make it ideal for supporting cell growth and tissue repair.
 

Simultaneously, the growing need for biomedical textiles, which enhance the healing process, is further boosting the PGS market. Biomedical textiles, incorporating materials like PGS, are used in wound care, surgical implants, and other medical applications where rapid and effective healing is critical. The versatility of PGS in forming complex structures and its ability to interact favourably with biological tissues align well with these trends, positioning it as an asset in both tissue engineering and advanced medical textiles, thereby driving market growth.
 

Polyglycerol Sebacate Market Trends

The polyglycerol Sebacate (PGS) industry is experiencing notable growth in the medical industry due to its advanced applications in tissue engineering and regenerative medicine. PGS’s biocompatibility, customizable degradation rates, and mechanical properties make it ideal for creating scaffolds and matrices that support tissue regeneration. Additionally, the rising demand for biomedical textiles, which utilize PGS for enhanced healing and improved surgical outcomes, further fuels market expansion. These trends underscore PGS’s growing role as a crucial material in developing innovative medical solutions and advancing patient care, positioning it favourably in the evolving healthcare landscape.
 

Polyglycerol Sebacate Market Analysis

The soft gel segment will capture USD 43.35 million and demonstrate a 9.6% CAGR by 2032. The polyglycerol sebacate (PGS) market is evolving with various product forms catering to diverse medical applications. Soft gels are increasingly popular due to their flexibility and biocompatibility, making them ideal for drug delivery systems and tissue scaffolding. PGS in paste form is gaining traction for its ease of application and customization, especially in regenerative medicine and wound care.
 

Extruded products, such as films and fibers, are widely used in biomedical textiles and implantable devices, providing structural support and controlled degradation properties. Other forms of PGS, including coatings and porous structures, are also emerging for specialized applications. Overall, the trend is towards leveraging PGS’s versatility across these forms to enhance functionality in medical devices, regenerative treatments, and advanced textile applications, thereby expanding its market presence.
 

The tissue engineering application segment held a 45% market share in 2023, amounting to USD 29.47 million, and is projected to grow at a 9% CAGR from 2024 to 2032. The polyglycerol sebacate market is witnessing significant growth across various applications. In tissue engineering, PGS is highly valued for its biocompatibility and customizable properties, making it ideal for creating scaffolds that support cell growth and tissue regeneration. The drug delivery sector benefits from PGS’s controlled degradation and flexibility, enabling innovative, targeted delivery systems.
 

In adhesives, PGS is used for its strong bonding and biocompatible features, essential for medical and surgical applications. The coatings segment leverages PGS for its ability to enhance the performance and longevity of implants and medical devices. Additionally, the others category includes diverse applications such as wound care and specialized biomedical textiles. Overall, these trends highlight PGS’s versatility and growing importance in advancing medical technology and improving patient outcomes.
 

The North America polyglycerol sebacate market is projected to achieve USD 74.34 million, with a CAGR of 12% from 2024 to 2032, owing to rise in old population and increase in lifestyle diseases such as obesity and others.
 

North America dominated the market due of prevalence of obesity and osteoarthritis patients along with higher spending on medical facilities especially in U.S. At present, Secant Group LLC is the only player in the PGS business, but it is estimated that companies operating in the biodegradable bone graft polymers space will enter the market soon. Rising demand and awareness from developing countries in Eastern Europe will fuel the growth of biomaterials.
 

Polyglycerol Sebacate Market Share

Companies include, Evonik Industries AG plays a crucial role in advancing PGS through its research and development of high-performance polymers, focusing on applications in tissue engineering and regenerative medicine. Sigma-Aldrich (Merck Group) supports the PGS market by providing high-quality PGS materials for research and industrial use, facilitating advancements in drug delivery systems and tissue scaffolds. PolySciTech (Akina, Inc.) specializes in biomedical polymers, offering customized PGS solutions for various applications, including tissue engineering and medical devices.
 

Cambridge Polymers Group develops tailored PGS formulations for specific medical uses, such as scaffolds and coatings, enhancing material performance. BASF SE contributes through its innovation in polymer chemistry, optimizing PGS for applications in biomedical textiles and coatings.
 

Polyglycerol Sebacate Market Companies

Top companies operating in the polyglycerol sebacate industry include:

• BASF SE
• Cambridge Polymers Group
• Evonik Industries AG
• Fuso Chemical Co., Ltd.
• Orthofix International NV
• Polymers LLC
• PolySciTech (Akina, Inc.)
• Resinex
• Secant LLC
• Sigma-Aldrich (Merck Group)
• Synthecon Inc.
   

Polyglycerol Sebacate Industry News

• July 2022: Secant Group is developing Hydralese (PGSU) (poly (glycerol sebacate) urethane) for use in drug-delivery devices. The company created Hydralese (PGSU) from crosslinking poly (glycerol sebacate) (PGS) using urethane chemistry and is marketing it under the Hydralese platform.
   
• June 2023: Merck, a prominent science and technology company, is enhancing its production capacity for highly purified reagents at its Nantong facility in China, a key transportation hub in the Yangtze River Delta. This investment of around USD 78.1 million will enable large-scale manufacturing of high-purity reagents for quality control and testing in the biopharma sector, significantly boosting annual output by several thousand tons.
   

The polyglycerol sebacate (PGS) market research report includes in-depth coverage of the industry, with estimates and forecasts in terms of revenue and volume (USD Billion) (Tons) from 2021 to 2032, for the following segments:

Click here to Buy Section of this Report

Market, By Form

• Soft gel
• Paste
• Extruded products
• Others

Market, By Application

• Tissue engineering
• Drug delivery
• Adhesives
• Coatings
• Others

The above information is provided for the following regions and countries:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Australia
• Latin America
  • Brazil
  • Mexico
• MEA
  • Saudi Arabia
  • UAE
  • South Africa