Nucleic Acid Isolation & Purification Market Analysis

Nucleic Acid Isolation & Purification Market Analysis

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Based on product, the market is segmented into reagents & kits and instruments. The reagents & kits segment is expected to lead the market, projecting revenue of USD 7.3 billion by 2032.
 

• The development of innovative reagents and kits with enhanced performance, automation capabilities, and compatibility with high-throughput systems has significantly contributed to the expansion of this segment. For instance, Thermo Fisher’s PrepSEQ 1-2-3 nucleic acid extraction kit rapidly extracts mycoplasma genomic DNA from 100 µL sample volumes. The kit is also optimized for use with the MycoSEQ mycoplasma detection kit.
   
• Similarly, the demand for kits used in the isolation and purification of nucleic acids is on the rise, driven by the increasing number of research studies focused on genome-based diseases.
   

Based on type, the nucleic acid isolation and purification market is classified into RNA isolation & purification and DNA isolation & purification. The RNA isolation & purification segment is further categorized into mRNA isolation & purification, miRNA isolation & purification, total RNA isolation & purification, and other RNA isolation & purification types. The RNA isolation & purification segment dominated the market accounting for the highest share of 52.6%. in 2023.
 

• High market share can be attributed to the expanding applications of RNA-based technologies, such as gene expression analysis, RNA sequencing, and emerging therapeutic modalities like RNA interference.
   
• Additionally, advent of RNA-based therapeutics, such as mRNA vaccines and gene therapies highlight the need for robust isolation and purification protocols, thus solidifying the high growth of the segment.
   

Based on method, the nucleic acid isolation & purification market is segmented into magnetic beads, column-based, reagent-based, and other methods. The magnetic beads segment dominated the market in 2023 and is projected to grow at a CAGR of 7.8% over the analysis period.
 

• The growing adoption of magnetic beads is owing to the advantage that it provides to researchers and scientists with improved assay performance and better isolation and purification of DNA and RNA.
   
• Additionally, its simplicity, speed, and adaptability to various sample types are few of the other key advantages associated with magnetic beads, thereby augmenting the market progression.
   

Based on application, the nucleic acid isolation and purification market is classified into diagnostics, drug discovery & development, precision medicine, and other applications. The diagnostics segment dominated the market accounting for the largest revenue in USD 1.7 billion in 2023.
 

• The large revenue share of the segment can be attributed to the rising application of DNA and RNA isolation for the identification of pathogens in routine sample processing.
   
• Also, laboratories, research institutions, and healthcare facilities including hospital settings are increasingly relying on advanced diagnostics based on nucleic acid analysis, driving the market's expansion.
   

Based on end-use, the nucleic acid isolation & purification market is classified into hospitals and diagnostic centers, pharmaceutical & biotechnology companies, contract research organizations, and other end-users. The hospitals and diagnostic centers segment dominated the market in 2023.
 

• Hospitals and diagnostic centers, being the frontline providers of healthcare services, invest heavily in cutting-edge technologies and equipment for nucleic acid isolation and purification. These setting serve as the primary facilities for patients undergoing major diagnostic tests, making them the focal point, thereby contribute significantly to their substantial market share.
   

 In 2023, North America held a significant business share of 37.8% in the nucleic acid isolation and purification market and is anticipated to dominate the market throughout the forecast period.
 

• The presence of leading biotechnology and pharmaceutical companies, coupled with significant government investments in genomics and molecular biology research, has propelled North America to the forefront of nucleic acid isolation and purification.
   
• Moreover, a high level of awareness among healthcare professionals and researchers, coupled with an increasing demand for personalized medicine and diagnostics, further accentuates the region's dominance in the market.