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High risk of health complications, such as Kawasaki disease (KD) related to the long-term consumption of large amounts of soy products is expected to hamper the isoflavones market demand. Soy isoflavones can be difficult to digest and can cause constipation, diarrhea, and other digestive problems. Additionally, isoflavones are also considered for reacting with certain treatments for conditions such as cystic fibrosis, kidney stones, and hyperthyroidism. The compound is also known to have certain side effects on female reproductive health with abnormal tissue growth in the uterus, and poor development of the reproductive system in case of long-term exposure to isoflavone genistein.