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Colorectal cancer is amongst the leading cause of morbidity and mortality globally. CRC accounts for 9.4% mortality rate that is the second-most lethal cause of cancer death after lung cancer. According to the NCBI article, in 2020, over 1.9 million new cases and 935,000 deaths from were reported associated with colorectal cancer globally. In some countries, the incidence and mortality associated with CRC are substantially high. This is majorly due to factors such as acceptance of westernized diet, lifestyle, and lack of healthcare infrastructure & resources, especially in the emerging economies. A study conducted by the Clinical and Translational Gastroenterology linked the rising incidence of obesity with surging prevalence of CRC. The prevalence is predicted to surge with increasing incidence of obesity among all age groups. With the obesity prevalence estimates set to multiply in the coming years, the prevalence of CRC to increase, further facilitating the in-vitro colorectal cancer screening tests market growth.
The early detection of CRC through in-vitro colorectal cancer screening tests is essential to reduce the disease burden and improve the mortality rate associated with CRC. Regular screening facilitates early detection that might lead to approximately 60% reduction in CRC mortalities. The use of in-vitro colorectal cancer screening tests is also projected to promote the average 5-year survival rate from 46% to 73%, with regular periodic screening every year.