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Gene vector industry revenue growth is driven by factors such as rising prevalence of genetic disorders, cancer, and infectious diseases, development of more advanced gene editing technologies, and increasing demand for personalized medicine. Gene vectors are necessary for the delivery of gene treatments into target cells in many instances of gene therapy, with viral vectors being among the most extensively studied vectors owing to their unique benefits, such as their exceptional transduction efficiency.
Various products using viral vectors to deliver therapeutic genes have been approved for use against cancer, infectious diseases, and monogenic disorders. Also, several clinical tests are currently being conducted to increase their therapeutic utility. Gene delivery methods rely on retrovirus, Adenovirus (Ad), poxvirus, Herpes Simplex Virus (HSV), and Adeno-Associated Virus (AAV) has been employed in over 66% of all gene therapy clinical trials to date. These viruses were initially used to build gene delivery systems because they are easily controlled in vitro and have been extensively investigated. Numerous characteristics of these viral vectors affect their potential for various therapeutic applications.