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Dermatologists were exploring the use of drug combinations and sequential therapy approaches to enhance treatment outcomes in certain skin conditions. Combining different classes of drugs or using them in a stepwise manner showed promise in achieving better disease control. In addition, biologic drugs, particularly monoclonal antibodies targeting specific cytokines or immune pathways, are gaining significant traction in the treatment of various autoimmune skin conditions. Drugs like TNF-alpha inhibitors, IL-17 inhibitors, and IL-23 inhibitors are becoming the standard of care for moderate to severe psoriasis and other inflammatory skin diseases due to their high efficacy and targeted approach.