Cell Isolation Market - By Product (Consumable, Instrument), Cell Type (Human, Animal), Cell Source (Bone Marrow, Adipose Tissue), Technique (Centrifugation), Application (Biomolecule Isolation, Cancer Research), End-user, Global Forecast, 2023-2032

Cell Isolation Market Size

Cell Isolation Market size was valued to be USD 5.2 billion in 2022 and is expected to reach USD 16.1 billion in 2032 with a CAGR of 12.1% from 2023 to 2032.The market is primarily driven by several key factors such as the rising prevalence of chronic and infectious diseases such as cancer and COVID-19, rising government support for cell-based research, growing emphasis on customized therapy and technical improvements.
 

Cell isolation and separation-related technological advances are anticipated to accelerate the market's growth. Moreover, rising research and development processes in the pharmaceutical and biotechnology sectors and the introduction of various advanced equipment and methodologies is expected to expand the market progress.

Cell isolation is the process of separating specific cells from a mixture of different cell types in a biological sample. It is aimed to extract the desired cells while maintaining their viability, integrity, and functional properties through various techniques. It is crucial for a number of applications, including the design and development of biologics, the production of therapeutic proteins, in-vitro diagnostics, and other applications in research, such as the collection of circulating tumour cells in the blood, the molecular analysis of particular cell populations, the isolation of immune cells from peripheral blood and the preparation of blood samples that have been separated from plasma.
 

COVID-19 Impact

The COVID-19 pandemic triggered an urgent need for research and diagnostics to understand the virus, its transmission, and its impact on the human body. This surge in demand for cell-based studies and diagnostic tests likely increased the demand for cell isolation products and technologies. In order to create innovative vaccines, treatments, and test kits, several pharmaceutical and biotech industrial giants have been engaged in quick and intensive R&D efforts. The need for cell separation technologies in research applications has been greatly increased as a result of the increased demands. The development of vaccines and treatment for SARS-CoV-2 virus led to a surge in research funding. This increasing fundings supported the cell isolation research and technology development. In addition to this, several pharmaceutical and biotech industry giants have been engaged in quick and intensive R&D efforts to develop novel vaccines, therapies, and testing kits. This factor greatly increased the need for cell separation technologies in research applications boosting the growth of this market.
 

Cell Isolation Market Driving Factors

The rising prevalence of chronic and infectious diseases, continuous expansion of biomedical research in areas such as cancer biology, regenerative medicine, immunology, and stem cell research has increased the demand for cell isolation tools, rapidly expanding demand for cell-based assays and screening platforms, cell-based therapies, focus on personalised medicines are the key factors for the growth of the market.
 

Cell isolation and separation-related advancements in technology are anticipated to accelerate the market trends. These developments may make products more effective and less expensive, which would encourage more people to use cell isolation tools like instruments and kits. For instance, Thermo Fisher Scientific unveiled the new Gibco CTS Xenon Electroporation System in March 2022, which is completely customisable and allows for the research and manufacture of cell therapies on a wide scale for clinical use. Therefore, over the projected period, such breakthroughs and product introductions are anticipated to fuel market expansion for cell isolation.
 

Cell Isolation Market Analysis

Based on the product, the cell isolation market is segmented into consumables and instruments. Consumables are further segmented into reagents, kits, media & sera, beads, and disposables. The instruments segment is divided into centrifuges, cell sorters, magnetic-activated cell separator systems, and filtration systems. Beads are further bifurcated into magnetic beads and fluorescent beads. In 2022, consumables held the largest market share of 62.2%. Consumables refer to the products and materials that are used up or depleted during the process of isolating cells from a biological sample. They play a critical role in the success of cell isolation procedures, and their quality can significantly impact the reliability and reproducibility of experimental results. Researchers and technicians working in the cell isolation field need to ensure that they use high-quality consumables that are compatible with their specific isolation protocols and cell.
 

Based on the cell type, the cell isolation market is classified into human cells and animal cells. Human cells are further subdivided into differentiated cells and stem cells. Due to increasing incidence of chronic and infectious diseases such as cancer, the human cells segment held the largest market share in 2022 and is expected to grow at CAGR of 12.2% during the forecast period. Differentiated cells are mature and specialized cells that have undergone a process of cellular differentiation, wherein they have developed specific structures and functions to perform specialized tasks in the body. Whereas stem cells are undifferentiated cells with the unique ability to self-renew and differentiate into various specialized cell types. These cells are isolated and utilized for various research, therapeutic, and diagnostic purposes.
 

Based on the cell source, the global cell isolation market is divided into bone marrow, adipose tissues, cord blood/ embryonic stem cells, and other cell sources. Bone marrow segment dominated the global cell isolation market and was valued at USD 2.5 billion in 2022. Bone marrow is a soft, spongy tissue found inside certain bones of the body. It is a vital part of the human hematopoietic system and plays a crucial role in the production of blood cells and immune cells. Due to rising cancer cases, bone marrow has been utilised in hematological malignancies, such as leukemia, lymphoma, and multiple myeloma. Bone marrow is involved in both the diagnosis and treatment of these cancers. As the cases of cancer, its diagnosis and treatment are increasing the bone marrow segment will rise further.
 

Based on the technique, the cell isolation market is fragmented into centrifugation-based cell isolation, surface-based cell isolation, and filtration-based cell isolation. In 2022, centrifugation-based cell isolation segment accounted for significant market share of 43.8% and is expected to grow at CAGR of 11.4% during the forecast timeframe. Centrifugation-based cell isolation is a commonly used method for separating different cell types from a heterogeneous cell population based on their density differences. This technique relies on the principle that cells with different densities will settle at different rates when subjected to centrifugal force. Due to its availability, affordability and global utilisation in institutes and research labs, this segment held the largest market share in 2022. The increasing demand for innovative techniques in research & development will drive the growth of this segment.
 

Based on the application, the cell isolation market is classified into biomolecule isolation, cancer research, stem cell therapy research, tissue regeneration/ regenerative medicines, in-vitro diagnostics, and other applications.  The biomolecule isolation segment is expected to grow at CAGR of 13.1% and is expected to reach USD 5.5 billion by 2032. Biomolecule isolation is a crucial process in cell isolation. It involves the separation and purification of specific biomolecules such as proteins, nucleic acids, lipids, and carbohydrates from complex biological samples. Isolating biomolecules allows to study their structure, function, and interactions, leading to a better understanding of biological processes and the development of new therapies and technologies. Moreover, rising need for high efficacious drugs in cancer and chronic diseases resistant to treatment, biomolecule isolation is rapidly increasing leading to the growth of the market.
 

Based on the end-user, the cell isolation market is divided into pharmaceutical & biotechnology companies, research & academic institutes, hospitals & diagnostic laboratories, and other end-users. In 2022, the pharmaceutical & biotechnology segment accounted for highest market share of 51.3%. Due to advancement in drug discovery and development, cell-based therapies, precision medicine, diagnostic assays and cell sorting techniques, the pharmaceutical & biotechnology companies are growing at a rapid pace. As modern technology continues to evolve, it will lead to even more significant breakthroughs in pharmaceutical and biotechnological segments.
 

In 2022, the North American cell isolation market held the largest share of 42.8%. It is due to a considerable increase patient pool of chronic diseases, government funding for cancer research and advancement of pharmaceutical & biotechnological sector. Additionally, the increasing prevalence of diseases, introduction of novel approaches in cell isolation, increasing research centers and labs, rising number of innovation equipment will increase the growth in this region.
 

Cell Isolation Market Share

The prominent players in the cell isolation market are:

• Thermo Fisher Scientific, Inc.
• Danaher Corporation,
• Merk KGaA
• Becton Dickinson & Company
• Agilent Technologies Inc.
• Terumo Corporation
• Bio-Rad Laboratories Inc.
• F. Hoffmann-La Roche Ltd,
• Corning Inc.
• STEMCELL Technologies Inc.
• Invent Biotechnologies
• Qiagen NV,
• Alfa Laval AB
• Sartorius AG
• Bio-Techne Corporation.

These companies are implementing several strategies such as collaborations, acquisitions, partnerships, mergers, and product launches to maintain a competitive edge in the industry.
 

Cell Isolation Market Industry News:

• In October 2022, Thermo Fisher Scientific, introduced DynaCellect, a next generation cell isolation, cell activation, cell depletion instrument. Moreover, to optimize the cell therapy manufacturing process, it launched Dynabeads magnetic beads removal instrument. This strategy helped the company to enhance their portfolio and revenue of the company.
   
• In May 2019, Thermo Fisher Scientific purchased Brammer Bio in order to increase its capacity to meet the rapidly expanding industry for gene and cell therapy. The two companies stated that they had signed a legally binding contract under which Thermo Fisher will buy Brammer Bio for around USD 1.7 billion in cash. Their position as a dependable partner to pharma and biotech will be strengthened by utilizing their combined talents, commercial size, and customer relationships to expand patient access to lifesaving drugs.

The cell isolation market report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments:

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Market Size, By Product

• Consumables
  • Reagents, kits, media & sera
  • Beads
    • Magnetic beads
    • Fluorescent beads
  • Disposables
• Instruments
  • Centrifuges
  • Cell sorters
  • Magnetic-activated cell separator systems
  • Filtration systems

Market Size, By Cell Type

• Human cells
  • Differentiated cells
  • Stem cells
• Animal cells

Market Size, By Cell Source

• Bone marrow
• Adipose tissues
• Cord blood/ embryonic stem cells
• Other cell sources

Market Size, By Technique

• Centrifugation-based cell isolation
• Surface-based cell isolation
• Filtration-based cell isolation

Market Size, By Application

• Biomolecule isolation
• Cancer research
• Stem cell research
• Tissue regeneration/ regenerative medicines
• In-vitro diagnostics
• Other applications

Market Size, By End-user

• Pharmaceutical & biotechnology companies
• Research & academic institutes
• Hospitals & diagnostic laboratories
• Other end-users

The above information is provided for the following regions and countries:

• North America 
  • U.S.
  • Canada
• Europe 
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Switzerland
  • Rest of Europe
• Asia Pacific 
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America 
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa 
  • South Africa
  • Saudi Arabia
  • Rest of Middle East & Africa